|Title||Secondary Amides as Hydrogen Atom Transfer Promoters for Reactions of Samarium Diiodide|
|Publication Type||Journal Article|
|Year of Publication||2017|
|Authors||Chciuk TV, Li AM, Vazquez-Lopez A, Anderson WR, Flowers, II RA|
Two secondary amides (N-methylacetamide and 2-pyrrolidinone) were used as additives with SmI2 in THF to estimate the extent of N–H bond weakening upon coordination. Mechanistic and synthetic studies demonstrate significant bond-weakening, providing a reagent system capable of reducing a range of substrates through formal hydrogen atom transfer.